| Index | Tuscumbia | Missouri | National |
| Average Test Scores | 35% | 44% | 48% |
| Student/Teacher ratio | n/a | 14:1 | 16:1 |
| Total public schools | n/a | 1,899 | 79,221 |
| Total private schools | n/a | 531 | 24,874 |
| Total post-secondary schools | n/a | 213 | 7,963 |
| Index | Tuscumbia | Missouri | National |
| Completed 8th grade | 67.0% | 86.0% | 84.3% |
| Completed high school | 63.7% | 84.2% | 83.0% |
| Completed some college | 31.9% | 57.7% | 59.4% |
| Completed associate degree | 11.0% | 35.2% | 38.5% |
| Completed bachelors | 7.7% | 27.6% | 30.3% |
| Completed masters | 3.8% | 10.4% | 11.5% |
| Completed professional degree | 0.5% | 2.8% | 3.3% |
| Completed doctorate | 0.0% | 1.2% | 1.3% |
There are a total of n/a public schools, n/a private schools and n/a post-secondary schools in Tuscumbia. Using the proficiency score averages, the average test scores for Tuscumbia, MO schools is 35%. The average student to teacher ratio is n/a. In Tuscumbia, MO, an average of 67.0% of students have completed 8th grade and an average of 63.7% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| St. Elizabeth, MO | 445 | 69% | 42.7% |
| Osage Beach, MO | 4,923 | 51% | 6.3% |
| Eldon, MO | 4,671 | 51% | 6.0% |
| Iberia, MO | 642 | 35% | 28.1% |
| Tuscumbia, MO | 162 | 35% | 27.6% |
| City | Population | Avg. Test Scores | National Avg. |
| Nebo, KY | 162 | 54% | 11.5% |
| Strasburg, MO | 162 | 47% | 2.1% |
| Dayville, OR | 162 | 50% | 4.2% |
| Shanksville, PA | 162 | 56% | 15.6% |
| Elkton, OR | 162 | 52% | 8.3% |
| Tuscumbia, MO | 162 | 35% | 27.6% |
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