| Month | Temp. (min) | Temp. (max) | Temp. (avg) | Precipitation |
| January | 33°F | 54°F | 42°F | 4.8" |
| February | 35°F | 57°F | 45°F | 3.2" |
| March | 44°F | 67°F | 54°F | 4.5" |
| April | 51°F | 76°F | 63°F | 4.9" |
| May | 59°F | 82°F | 70°F | 4.3" |
| June | 67°F | 91°F | 78°F | 4.2" |
| July | 70°F | 92°F | 80°F | 5.3" |
| August | 69°F | 92°F | 79°F | 4.5" |
| September | 62°F | 86°F | 73°F | 3.8" |
| October | 50°F | 76°F | 62°F | 3.9" |
| November | 40°F | 65°F | 52°F | 3.6" |
| December | 36°F | 56°F | 45°F | 5.6" |
| Index | Tuscumbia | Alabama | National |
| Air quality index | 37 | 37 | 42 |
| Pollution index | 321,318 | 3,012,339 | 2,726,193 |
| Measurement | Total |
| Days measured | 263 |
| Days with good air quality | 252 |
| Days with moderate air quality | 11 |
| Days w/ poor A.Q. for sensitive groups | 0 |
| Days with unhealthy air quality | 0 |
| Pollutant | Total |
| Arsenic | 0.000% |
| Benzene | 0.010% |
| Carbon Tetrachloride | 0.001% |
| Lead | 0.000% |
| Mercury | 0.000% |
| City | Population | Air Quality Index | National Avg. |
| Littleville, AL | 949 | 37 | 26.0% |
| Sheffield, AL | 8,925 | 37 | 26.0% |
| Leighton, AL | 789 | 37 | 26.0% |
| Muscle Shoals, AL | 14,379 | 37 | 26.0% |
| Underwood-Petersville, AL | 2,707 | 37 | 26.0% |
| Tuscumbia, AL | 8,445 | 37 | 26.0% |
| City | Population | Air Quality Index | National Avg. |
| Nicolet, QC | 8,446 | n/a | |
| Tuskegee, AL | 8,443 | 52 | 4.0% |
| Mason, MI | 8,441 | 36 | 28.0% |
| Carbondale, PA | 8,438 | 38 | 24.0% |
| Mascoutah, IL | 8,454 | 54 | 8.0% |
| Tuscumbia, AL | 8,445 | 37 | 26.0% |
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