There are many appealing neighborhoods in San Mateo, but finding the right one if you’re a young professional can definitely be tricky. Listed below are the best neighborhoods in San Mateo for singles and young professionals for 2024. To calculate our rankings we used the following criteria: median age, people between the ages of 25-34, local amenities (bars, restaurants, grocery stores, coffee shops, etc.), employment opportunities, housing affordability and crime rates.