| Statistic | Little Italy | San Diego | California |
| Population | 2,942 | 1,414,545 | 39,512,223 |
| Population density (sq mi) | 6,434 | 4,341 | 256 |
| Median age | 38.5 | 35.2 | 36.0 |
| Male/Female ratio | 1.1:1 | 1.0:1 | 1.0:1 |
| Married (15yrs & older) | n/a | 49% | 52% |
| Families w/ Kids under 18 | 12% | 43% | 46% |
| Speak English | n/a | 60% | 56% |
| Speak Spanish | n/a | 22% | 29% |
| Race | Little Italy | San Diego | California |
| White | 75.23% | 61.95% | 61.26% |
| Black | 3.21% | 6.09% | 5.85% |
| Asian | 10.33% | 17.25% | 13.85% |
| American Indian | 0.52% | 0.52% | 0.74% |
| Native Hawaiian | 0.00% | 0.42% | 0.39% |
| Mixed race | 6.79% | 7.77% | 4.62% |
| Other race | 3.93% | 5.99% | 13.28% |
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