| Index | Puxico | Missouri | National |
| Average Test Scores | 31% | 44% | 48% |
| Student/Teacher ratio | 26:1 | 14:1 | 16:1 |
| Total public schools | 3 | 1,899 | 79,221 |
| Total private schools | n/a | 531 | 24,874 |
| Total post-secondary schools | n/a | 213 | 7,963 |
| Index | Puxico | Missouri | National |
| Completed 8th grade | 77.0% | 86.0% | 84.3% |
| Completed high school | 73.5% | 84.2% | 83.0% |
| Completed some college | 43.7% | 57.7% | 59.4% |
| Completed associate degree | 24.7% | 35.2% | 38.5% |
| Completed bachelors | 19.0% | 27.6% | 30.3% |
| Completed masters | 7.9% | 10.4% | 11.5% |
| Completed professional degree | 1.2% | 2.8% | 3.3% |
| Completed doctorate | 0.8% | 1.2% | 1.3% |
There are a total of 3 public schools, n/a private schools and n/a post-secondary schools in Puxico. Using the proficiency score averages, the average test scores for Puxico, MO schools is 31%. The average student to teacher ratio is 26:1. In Puxico, MO, an average of 77.0% of students have completed 8th grade and an average of 73.5% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Poplar Bluff, MO | 16,979 | 56% | 16.3% |
| Bloomfield, MO | 2,404 | 55% | 13.9% |
| Advance, MO | 1,430 | 47% | 2.1% |
| Zalma, MO | 60 | 45% | 5.7% |
| Dexter, MO | 7,867 | 45% | 5.9% |
| Puxico, MO | 1,133 | 31% | 35.4% |
| City | Population | Avg. Test Scores | National Avg. |
| Steele, AL | 1,133 | 62% | 29.2% |
| Wickes, AR | 1,133 | 57% | 18.8% |
| Cottonwood, AL | 1,133 | 46% | 4.2% |
| Morningside, MD | 1,132 | 27% | 43.2% |
| Onarga, IL | 1,134 | 33% | 32.3% |
| Puxico, MO | 1,133 | 31% | 35.4% |
Here are the best places to live in Missouri
Check out the 10 most dangerous cities in Missouri
See the best places to live in Puxico
These are the 10 cheapest cities in Missouri