| Index | Potosi | Missouri | National |
| Average Test Scores | 59% | 44% | 48% |
| Student/Teacher ratio | 14:1 | 14:1 | 16:1 |
| Total public schools | 7 | 1,899 | 79,221 |
| Total private schools | n/a | 531 | 24,874 |
| Total post-secondary schools | n/a | 213 | 7,963 |
| Index | Potosi | Missouri | National |
| Completed 8th grade | 71.7% | 86.0% | 84.3% |
| Completed high school | 63.4% | 84.2% | 83.0% |
| Completed some college | 44.2% | 57.7% | 59.4% |
| Completed associate degree | 23.0% | 35.2% | 38.5% |
| Completed bachelors | 14.1% | 27.6% | 30.3% |
| Completed masters | 4.8% | 10.4% | 11.5% |
| Completed professional degree | 0.3% | 2.8% | 3.3% |
| Completed doctorate | 0.3% | 1.2% | 1.3% |
There are a total of 7 public schools, n/a private schools and n/a post-secondary schools in Potosi. Using the proficiency score averages, the average test scores for Potosi, MO schools is 59%. The average student to teacher ratio is 14:1. In Potosi, MO, an average of 71.7% of students have completed 8th grade and an average of 63.4% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Bonne Terre, MO | 7,037 | 50% | 3.1% |
| Park Hills, MO | 8,512 | 48% | 0.3% |
| Leadwood, MO | 1,579 | 45% | 6.3% |
| Desloge, MO | 4,901 | 45% | 6.9% |
| De Soto, MO | 6,359 | 42% | 13.5% |
| Potosi, MO | 2,572 | 59% | 22.9% |
| City | Population | Avg. Test Scores | National Avg. |
| Wilburton, OK | 2,572 | 33% | 31.6% |
| Covington, IN | 2,572 | 57% | 18.4% |
| Crisfield, MD | 2,572 | 35% | 26.6% |
| Apalachicola, FL | 2,572 | 61% | 27.1% |
| North Falmouth, MA | 2,572 | 72% | 50.0% |
| Potosi, MO | 2,572 | 59% | 22.9% |
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