| Statistic | Lake Nona South | Orlando | Florida |
| Population | 3,053 | 284,817 | 21,477,737 |
| Population density (sq mi) | 107 | 2,569 | 410 |
| Median age | 37.0 | 33.9 | 41.6 |
| Male/Female ratio | 0.9:1 | 0.9:1 | 1.0:1 |
| Married (15yrs & older) | n/a | 42% | 54% |
| Families w/ Kids under 18 | 46% | 46% | 38% |
| Speak English | n/a | 61% | 72% |
| Speak Spanish | n/a | 27% | 21% |
| Race | Lake Nona South | Orlando | Florida |
| White | 73.01% | 57.42% | 75.90% |
| Black | 5.53% | 24.20% | 16.14% |
| Asian | 10.98% | 4.65% | 2.61% |
| American Indian | 0.00% | 0.14% | 0.27% |
| Native Hawaiian | 0.00% | 0.02% | 0.06% |
| Mixed race | 9.35% | 8.06% | 2.48% |
| Other race | 1.13% | 5.52% | 2.54% |
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