| Month | Temp. (min) | Temp. (max) | Temp. (avg) | Precipitation |
| January | 17°F | 39°F | 27°F | 0.6" |
| February | 20°F | 43°F | 30°F | 0.9" |
| March | 33°F | 58°F | 44°F | 2.0" |
| April | 43°F | 68°F | 54°F | 4.3" |
| May | 53°F | 77°F | 64°F | 4.6" |
| June | 64°F | 86°F | 75°F | 6.0" |
| July | 67°F | 89°F | 78°F | 4.0" |
| August | 64°F | 87°F | 75°F | 4.7" |
| September | 56°F | 81°F | 67°F | 3.5" |
| October | 44°F | 69°F | 55°F | 3.1" |
| November | 32°F | 56°F | 43°F | 1.5" |
| December | 21°F | 40°F | 30°F | 1.9" |
| Index | Mound City | Missouri | National |
| Air quality index | 43 | 97 | 42 |
| Pollution index | 2,582,160 | 1,630,255 | 2,726,193 |
| Measurement | Total |
| Days measured | 365 |
| Days with good air quality | 283 |
| Days with moderate air quality | 82 |
| Days w/ poor A.Q. for sensitive groups | 0 |
| Days with unhealthy air quality | 0 |
| Pollutant | Total |
| Arsenic | 0.030% |
| Benzene | 0.030% |
| Carbon Tetrachloride | 0.004% |
| Lead | 0.010% |
| Mercury | 0.010% |
| City | Population | Air Quality Index | National Avg. |
| Bigelow, MO | 3 | 43 | 14.0% |
| Forest City, MO | 266 | 43 | 14.0% |
| Oregon, MO | 963 | 43 | 14.0% |
| Preston, NE | 30 | 43 | 14.0% |
| Big Lake, MO | 75 | 43 | 14.0% |
| Mound City, MO | 1,150 | 43 | 14.0% |
| City | Population | Air Quality Index | National Avg. |
| Dunnavant, AL | 1,150 | 53 | 6.0% |
| Bethany Beach, DE | 1,150 | 36 | 28.0% |
| Windsor, IL | 1,150 | 40 | 20.0% |
| Cottage City, MD | 1,150 | 47 | 6.0% |
| Ninnekah, OK | 1,150 | 43 | 14.0% |
| Mound City, MO | 1,150 | 43 | 14.0% |
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