| Statistic | Macksville | Kansas | National |
| Population | 570 | 2,913,314 | 328,239,523 |
| Population density (sq mi) | 571 | 36 | 91 |
| Median age | 40.3 | 36.2 | 37.7 |
| Male/Female ratio | 1.2:1 | 1.0:1 | 1.0:1 |
| Married (15yrs & older) | 71% | 59% | 55% |
| Families w/ Kids under 18 | 43% | 45% | 43% |
| Speak English | 71% | 89% | 79% |
| Speak Spanish | 29% | 8% | 13% |
| Race | Macksville | Kansas | National |
| White | 79.82% | 85.19% | 73.35% |
| Black | 0.00% | 5.79% | 12.63% |
| Asian | 0.00% | 2.68% | 5.22% |
| American Indian | 3.51% | 0.82% | 0.82% |
| Native Hawaiian | 0.00% | 0.06% | 0.18% |
| Mixed race | 14.39% | 3.31% | 3.06% |
| Other race | 2.28% | 2.15% | 4.75% |
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