| Index | Knoxville | Illinois | National |
| Average Test Scores | 25% | 33% | 48% |
| Student/Teacher ratio | 19:1 | 18:1 | 16:1 |
| Total public schools | 3 | 3,938 | 79,221 |
| Total private schools | n/a | 1,438 | 24,874 |
| Total post-secondary schools | n/a | 306 | 7,963 |
| Index | Knoxville | Illinois | National |
| Completed 8th grade | 90.5% | 86.2% | 84.3% |
| Completed high school | 89.0% | 84.7% | 83.0% |
| Completed some college | 54.2% | 61.8% | 59.4% |
| Completed associate degree | 28.7% | 40.7% | 38.5% |
| Completed bachelors | 18.1% | 32.9% | 30.3% |
| Completed masters | 6.4% | 12.7% | 11.5% |
| Completed professional degree | 0.6% | 3.4% | 3.3% |
| Completed doctorate | 0.0% | 1.2% | 1.3% |
There are a total of 3 public schools, n/a private schools and n/a post-secondary schools in Knoxville. Using the proficiency score averages, the average test scores for Knoxville, IL schools is 25%. The average student to teacher ratio is 19:1. In Knoxville, IL, an average of 90.5% of students have completed 8th grade and an average of 89.0% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Williamsfield, IL | 509 | 44% | 8.3% |
| London Mills, IL | 326 | 38% | 20.5% |
| Oneida, IL | 778 | 36% | 25.5% |
| Farmington, IL | 1,939 | 32% | 33.3% |
| Abingdon, IL | 3,570 | 27% | 43.2% |
| Knoxville, IL | 3,137 | 25% | 47.2% |
| City | Population | Avg. Test Scores | National Avg. |
| Milbank, SD | 3,137 | 51% | 6.3% |
| Mamou, LA | 3,137 | 77% | 59.9% |
| Zillah, WA | 3,137 | 57% | 19.5% |
| Elgin, OK | 3,137 | 38% | 20.8% |
| Cleveland, OK | 3,138 | 27% | 43.8% |
| Knoxville, IL | 3,137 | 25% | 47.2% |
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