| Month | Temp. (min) | Temp. (max) | Temp. (avg) | Precipitation |
| January | 17°F | 33°F | 24°F | 4.0" |
| February | 17°F | 35°F | 26°F | 2.3" |
| March | 27°F | 45°F | 35°F | 2.8" |
| April | 38°F | 61°F | 49°F | 4.7" |
| May | 49°F | 72°F | 60°F | 5.0" |
| June | 59°F | 81°F | 70°F | 7.1" |
| July | 61°F | 81°F | 71°F | 5.8" |
| August | 61°F | 81°F | 71°F | 8.7" |
| September | 55°F | 77°F | 66°F | 5.9" |
| October | 46°F | 65°F | 55°F | 5.0" |
| November | 33°F | 50°F | 41°F | 4.9" |
| December | 23°F | 37°F | 30°F | 2.2" |
| Index | Knox | Indiana | National |
| Air quality index | 37 | 56 | 42 |
| Pollution index | 898,555 | 2,719,453 | 2,726,193 |
| Measurement | Total |
| Days measured | 364 |
| Days with good air quality | 305 |
| Days with moderate air quality | 55 |
| Days w/ poor A.Q. for sensitive groups | 4 |
| Days with unhealthy air quality | 0 |
| Pollutant | Total |
| Arsenic | 0.001% |
| Benzene | 0.020% |
| Carbon Tetrachloride | 0.004% |
| Lead | 0.005% |
| Mercury | 0.000% |
| City | Population | Air Quality Index | National Avg. |
| La Crosse, IN | 517 | 37 | 26.0% |
| San Pierre, IN | 248 | 37 | 26.0% |
| Hanna, IN | 198 | 37 | 26.0% |
| Wanatah, IN | 1,198 | 37 | 26.0% |
| Medaryville, IN | 712 | 37 | 26.0% |
| Knox, IN | 3,553 | 37 | 26.0% |
| City | Population | Air Quality Index | National Avg. |
| Lely, FL | 3,553 | 34 | 32.0% |
| St. Anthony, ID | 3,552 | 43 | 14.0% |
| Fetters Hot Springs-Agua Caliente, CA | 3,554 | 35 | 30.0% |
| Kimberly, AL | 3,551 | 53 | 6.0% |
| Pen Argyl, PA | 3,551 | 34 | 32.0% |
| Knox, IN | 3,553 | 37 | 26.0% |
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