| Month | Temp. (min) | Temp. (max) | Temp. (avg) | Precipitation |
| January | 37°F | 55°F | 45°F | 5.4" |
| February | 37°F | 57°F | 46°F | 3.6" |
| March | 46°F | 69°F | 56°F | 3.3" |
| April | 54°F | 76°F | 65°F | 4.4" |
| May | 63°F | 83°F | 72°F | 4.7" |
| June | 70°F | 92°F | 80°F | 2.0" |
| July | 72°F | 92°F | 81°F | 4.3" |
| August | 72°F | 94°F | 82°F | 3.2" |
| September | 66°F | 87°F | 75°F | 8.2" |
| October | 53°F | 77°F | 64°F | 6.2" |
| November | 44°F | 67°F | 54°F | 2.5" |
| December | 38°F | 57°F | 46°F | 6.3" |
| Index | Isola | Mississippi | National |
| Air quality index | 43 | 40 | 42 |
| Pollution index | 582,214 | 1,514,109 | 2,726,193 |
| Measurement | Total |
| Days measured | 364 |
| Days with good air quality | 270 |
| Days with moderate air quality | 94 |
| Days w/ poor A.Q. for sensitive groups | 0 |
| Days with unhealthy air quality | 0 |
| Pollutant | Total |
| Arsenic | 0.000% |
| Benzene | 0.020% |
| Carbon Tetrachloride | 0.001% |
| Lead | 0.004% |
| Mercury | 0.000% |
| City | Population | Air Quality Index | National Avg. |
| Moorhead, MS | 1,513 | 43 | 14.0% |
| Hollandale, MS | 1,980 | 43 | 14.0% |
| Morgan City, MS | 264 | 43 | 14.0% |
| Indianola, MS | 9,258 | 43 | 14.0% |
| Silver City, MS | 365 | 43 | 14.0% |
| Isola, MS | 770 | 43 | 14.0% |
| City | Population | Air Quality Index | National Avg. |
| Tuttletown, CA | 770 | 39 | 22.0% |
| Kosse, TX | 770 | 38 | 24.0% |
| Oakwood, TX | 770 | 41 | 18.0% |
| Saint-Étienne-de-Bolton, QC | 770 | n/a | |
| Mignon, AL | 771 | 38 | 24.0% |
| Isola, MS | 770 | 43 | 14.0% |
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