| Statistic | Reportedincidents | /100k people | Guthrie/100k people | Oklahoma/100k people | National/100k people |
| Total crime | 213 | n/a (estimate) | 1,835 | 2,401 | 2,119 |
| Murder | 0 | n/a | 0.0 | 6.3 | 5.0 |
| Rape | 7 | n/a | 60.3 | 59.7 | 37.5 |
| Robbery | 1 | n/a | 8.6 | 38.2 | 60.6 |
| Assault | 11 | n/a | 94.8 | 318.7 | 256.1 |
| Violent crime | 19 | n/a (estimate) | 164 | 423 | 359 |
| Burglary | 21 | n/a | 180.9 | 411.4 | 229.2 |
| Theft | 151 | n/a | 1,300.7 | 1,343.7 | 1,272.1 |
| Vehicle theft | 22 | n/a | 189.5 | 222.6 | 258.8 |
| Property crime | 194 | n/a (estimate) | 1,671 | 1,978 | 1,760 |

The Guthrie crime rates are 13.4% lower than the national average. There are two main categories of crime - violent crime and property crime. Violent crime consists of murder, rape, robbery and assault, while property crimes include burglary, theft and vehicle theft. There were a total of 19 violent crimes in Guthrie (164 per 100,000 people), which is 54.4% lower than the national average and there were a total of 194 property crimes (1671 per 100,000 residents) which is 5.1% lower than average.
Guthrie showcased a dedication to violent crime safety in its latest reported crime year by achieving a murder rate of 0. This accomplishment could indicate that it is a safe place for residents, but also provides a shining example to other urban areas endeavoring to create safer communities.
Guthrie maintains a property crime rate that closely resembles the national norm. In Guthrie, 1671 property crimes were reported, aligning with the national average of 1760 per 100,000 individuals. Consequently, the area's safety profile stands on par with the average city, neither significantly safer nor more dangerous. This consistency underscores a balanced commitment to community safety and security, providing residents with a stable and reassuring living environment.
AreaVibes surveyed 8 local residents in Guthrie to gauge the safety of the area. Based on the results, 63% of people answered that there was very little crime in Guthrie and that they felt very comfortable walking alone at night. Another 38% of people responded that there was far too much crime and they would be hesitant to walk the streets alone at night. Keep in mind that the opinions of residents may vary depending on which area they live in.
To determine if Guthrie is a safe place to live, let's take a look at the overall crime rate of the area, as well as the number of daily crimes. Guthrie has a total crime rate that is 13% lower than the national average per 100,000 residents. This results in a total of 0.58 daily crimes (0.05 violent daily crimes and 0.53 daily property crimes) in Guthrie.
Year-over-year crime data allows residents and potential residents to assess the crime in Guthrie. A decrease in crime rates may indicate improving safety, while an increase could raise concerns. The year-over-year crime rate in Guthrie has decreased by 30.6%. Violent crimes have decreased by 51.3%, while property crimes have decreased by 27.6%. By comparing crime rates from one year to the next, authorities and communities can identify trends and patterns in criminal activity. This helps in understanding whether crime is increasing, decreasing, or remaining stable over time.
High population density areas are often large urban centers with diverse economic opportunities. These areas can exacerbate income inequality, with pockets of poverty existing alongside affluence. Areas with economic disparities may experience higher property crimes and, in some cases, violent crimes. On the other hand, areas with low population density tend to see lower Guthrie crime rates. The population density in Guthrie is 621.4 people per square mile, while the national average is 90.6 people per square mile.
The level of education within a community can impact crime rates. Higher educational attainment often correlates with lower crime rates, as it provides individuals with better job opportunities and alternatives to criminal behavior. While lower educational achievement rates tend to lead to higher crime rates. In Guthrie, 82.6% of people have completed high school, while 83% of people have completed high school nationally.
Rising cost of living expenses, including increased housing costs, grocery, utility and healthcare expenditures, can induce financial strain on individuals and families, particularly those with limited financial resources. Such economic stress may propel individuals towards crime, including theft or burglary, as a means of addressing their financial hardships. Conversely, cities characterized by a lower cost of living may alleviate economic pressures, potentially resulting in a reduced crime rate. In Guthrie, the cost of living is 12.35% lower than the national average, reflecting a more affordable economic environment that could contribute to a decrease in crime levels.

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| Item | Guthrie | Oklahoma | National |
| Law enforcement employees (officers & civilians) | 27 | 6,557 | 558,732 |
| Police officers & civilians /1000 residents | 2.6 | 3.4 | 3.3 |
| State | Total offenders | Oklahoma /100K | National /100K |
| Oklahoma | 7,097 | 203 | 266 |
| City | Population | Violent crime/100k people | Property crime/100k people | Total crime/100k people |
| Crescent, OK | 1,420 | 143 | 501 | 644 |
| Cashion, OK | 1,330 | 213 | 533 | 746 |
| Luther, OK | 1,608 | 433 | 371 | 803 |
| Cedar Valley, OK | 486 | 171 | 799 | 970 |
| Arcadia, OK | 139 | 0 | 1,136 | 1,136 |
| Langston, OK | 1,466 | 237 | 1,110 | 1,348 |
| Cimarron City, OK | 193 | 238 | 1,114 | 1,352 |
| Guthrie, OK | 11,666 | 164 | 1,671 | 1,835 |
| City | Population | Violent crime/100k people | Property crime/100k people | Total crime/100k people |
| Fort Morgan, CO | 11,666 | 285 | 1,980 | 2,265 |
| Minnehaha, WA | 11,665 | 265 | 2,002 | 2,267 |
| Endwell, NY | 11,668 | 449 | 2,034 | 2,484 |
| Bellmawr, NJ | 11,664 | 58 | 1,593 | 1,651 |
| Show Low, AZ | 11,670 | 737 | 2,261 | 2,998 |
| Guthrie, OK | 11,666 | 164 | 1,671 | 1,835 |