| Index | East Prairie | Missouri | National |
| Cost of living | 77 | 88 | 100 |
| Goods & Services | 94 | 92 | 100 |
| Groceries | 97 | 95 | 100 |
| Health care | 87 | 90 | 100 |
| Housing | 43 | 78 | 100 |
| Transportation | 89 | 91 | 100 |
| Utilities | 86 | 99 | 100 |
| Cost of living index | |
| Goods & Services index | |
| Groceries index | |
| Health care index | |
| Housing index | |
| Transportation index | |
| Utilities index |
| Median Income | Per Year | Per Month | Max Budget (28% DTI) | Max Budget (36% DTI) |
| Owners | $37,841 | $3,153 | $883 | $1,135 |
| Renters | $21,059 | $1,755 | $491 | $632 |
| State | General Sales Tax | With Max Surtax |
| Missouri | 4.225% | 10.85% |
| State | Income Tax (Low) | Income Tax (High) |
| Missouri | 2% | 4.95% |
| Item | East Prairie | National avg. | Difference |
| Haircut | $24.01 | $24.26 | 1.0% |
| Beauty Salon | $33.55 | $45.56 | 26.4% |
| Toothpaste | $3.74 | $3.70 | 1.1% |
| Shampoo | $1.08 | $1.28 | 15.9% |
| Movie | $11.93 | $12.13 | 1.7% |
| Bowling | $12.50 | $18.00 | 30.6% |
| Item | East Prairie | National avg. | Difference |
| Ground Beef | $5.94 | $5.84 | 1.7% |
| Fried Chicken | $1.67 | $1.57 | 6.2% |
| Milk | $4.54 | $4.67 | 2.8% |
| Potatoes | $5.03 | $4.93 | 1.9% |
| Pizza | $12.00 | $12.09 | 0.7% |
| Beer | $9.74 | $10.41 | 6.5% |
| Item | East Prairie | National avg. | Difference |
| Optometrist | $127.08 | $125.68 | 1.1% |
| Doctor | $138.39 | $135.78 | 1.9% |
| Dentist | $86.67 | $113.29 | 23.5% |
| Ibuprofen | $10.10 | $10.65 | 5.2% |
| Lipitor | $338.33 | $468.60 | 27.8% |
| Item | East Prairie | National avg. | Difference |
| Home Price | $65,000.00 | $184,700.00 | 64.8% |
| Avg. Mortgage Payment | $1,691.70 | $2,346.69 | 27.9% |
| Apartment Rent | $591.00 | $949.00 | 37.7% |
| Item | East Prairie | National avg. | Difference |
| Gasoline | $3.15 | $3.46 | 9.0% |
| Tire Balancing | $50.50 | $59.92 | 15.7% |
| Item | East Prairie | National avg. | Difference |
| All Electricity | $148.29 | $193.99 | 23.6% |
| Phone | $192.18 | $192.25 | 0.0% |
| City | Population | Cost of Living Index | National Avg. |
| North Lilbourn, MO | 187 | 92 | 8.0% |
| Pinhook, MO | 0 | 92 | 8.0% |
| Wilson City, MO | 24 | 73 | 27.5% |
| Wyatt, MO | 280 | 74 | 26.0% |
| Hickman, KY | 2,005 | 75 | 24.9% |
| East Prairie, MO | 2,980 | 77 | 22.6% |
| City | Population | Cost of Living Index | National Avg. |
| Bal Harbour, FL | 2,980 | 240 | 139.9% |
| Delphi, IN | 2,979 | 86 | 13.5% |
| Chevy Chase, MD | 2,979 | 258 | 158.4% |
| Lead, SD | 2,979 | 93 | 6.9% |
| Summit Hill, PA | 2,981 | 90 | 9.8% |
| East Prairie, MO | 2,980 | 77 | 22.6% |
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