| Index | Defiance | Ohio | National |
| Average Test Scores | 70% | 61% | 48% |
| Student/Teacher ratio | 17:1 | 17:1 | 16:1 |
| Total public schools | 14 | 3,650 | 79,221 |
| Total private schools | 4 | 1,000 | 24,874 |
| Total post-secondary schools | 1 | 393 | 7,963 |
| Index | Defiance | Ohio | National |
| Completed 8th grade | 85.3% | 86.9% | 84.3% |
| Completed high school | 84.5% | 85.6% | 83.0% |
| Completed some college | 47.9% | 55.7% | 59.4% |
| Completed associate degree | 28.2% | 35.1% | 38.5% |
| Completed bachelors | 18.9% | 26.7% | 30.3% |
| Completed masters | 6.2% | 10.0% | 11.5% |
| Completed professional degree | 1.1% | 2.7% | 3.3% |
| Completed doctorate | 0.5% | 1.1% | 1.3% |
There are a total of 14 public schools, 4 private schools and 1 post-secondary schools in Defiance. Using the proficiency score averages, the average test scores for Defiance, OH schools is 70%. The average student to teacher ratio is 17:1. In Defiance, OH, an average of 85.3% of students have completed 8th grade and an average of 84.5% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Miller City, OH | 142 | 87% | 80.9% |
| Continental, OH | 1,408 | 81% | 68.2% |
| Holgate, OH | 1,149 | 77% | 60.4% |
| Napoleon, OH | 8,310 | 74% | 53.6% |
| Bryan, OH | 8,243 | 69% | 43.2% |
| Defiance, OH | 16,741 | 70% | 46.3% |
| City | Population | Avg. Test Scores | National Avg. |
| Seagoville, TX | 16,726 | 54% | 11.5% |
| Clayton, MO | 16,763 | 73% | 52.7% |
| Cohoes, NY | 16,708 | 52% | 8.5% |
| Farmingville, NY | 16,705 | 63% | 30.2% |
| Sunnyside, WA | 16,703 | 45% | 6.4% |
| Defiance, OH | 16,741 | 70% | 46.3% |
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