| Month | Temp. (min) | Temp. (max) | Temp. (avg) | Precipitation |
| January | 31°F | 49°F | 39°F | 3.2" |
| February | 33°F | 51°F | 41°F | 2.3" |
| March | 43°F | 63°F | 52°F | 4.2" |
| April | 52°F | 74°F | 62°F | 4.3" |
| May | 61°F | 81°F | 70°F | 5.4" |
| June | 70°F | 91°F | 80°F | 3.0" |
| July | 72°F | 91°F | 81°F | 2.7" |
| August | 70°F | 90°F | 79°F | 2.3" |
| September | 62°F | 85°F | 72°F | 2.3" |
| October | 51°F | 75°F | 62°F | 2.9" |
| November | 41°F | 62°F | 51°F | 3.6" |
| December | 35°F | 52°F | 42°F | 4.5" |
| Index | Caruthersville | Missouri | National |
| Air quality index | 26 | 97 | 42 |
| Pollution index | 2,081,500 | 1,630,255 | 2,726,193 |
| Measurement | Total |
| Days measured | 360 |
| Days with good air quality | 341 |
| Days with moderate air quality | 19 |
| Days w/ poor A.Q. for sensitive groups | 0 |
| Days with unhealthy air quality | 0 |
| Pollutant | Total |
| Arsenic | 0.001% |
| Benzene | 0.020% |
| Carbon Tetrachloride | 0.002% |
| Lead | 0.010% |
| Mercury | 0.000% |
| City | Population | Air Quality Index | National Avg. |
| Hayti, MO | 2,380 | 26 | 48.0% |
| Pascola, MO | 78 | 26 | 48.0% |
| Cooter, MO | 347 | 26 | 48.0% |
| Holland, MO | 138 | 26 | 48.0% |
| Hayti Heights, MO | 359 | 26 | 48.0% |
| Caruthersville, MO | 5,518 | 26 | 48.0% |
| City | Population | Air Quality Index | National Avg. |
| Ulysses, KS | 5,518 | 15 | 70.0% |
| Connell, WA | 5,518 | 37 | 26.0% |
| Hooksett, NH | 5,517 | 37 | 26.0% |
| McKenzie, TN | 5,517 | 27 | 46.0% |
| Waterville, OH | 5,519 | 40 | 20.0% |
| Caruthersville, MO | 5,518 | 26 | 48.0% |
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