| Statistic | Seneca | Buffalo | New York |
| Population | 2,907 | 255,805 | 19,453,561 |
| Population density (sq mi) | 3,639 | 6,335 | 413 |
| Median age | 45.9 | 33.4 | 38.2 |
| Male/Female ratio | 1.0:1 | 0.9:1 | 0.9:1 |
| Married (15yrs & older) | n/a | 37% | 52% |
| Families w/ Kids under 18 | 44% | 47% | 43% |
| Speak English | n/a | 81% | 70% |
| Speak Spanish | n/a | 8% | 15% |
| Race | Seneca | Buffalo | New York |
| White | 83.16% | 47.11% | 64.31% |
| Black | 7.06% | 35.17% | 15.60% |
| Asian | 1.31% | 6.30% | 8.12% |
| American Indian | 1.93% | 0.50% | 0.38% |
| Native Hawaiian | 0.00% | 0.06% | 0.04% |
| Mixed race | 0.71% | 5.34% | 2.93% |
| Other race | 5.83% | 5.53% | 8.62% |
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